Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Mitophagy is down-regulated in human and mouse DMD and in other neuromuscular dystrophies.
  • Fig. S2. UA recovered mitophagy, mitochondrial, and muscle morphology in DMD worm models.
  • Fig. S3. UA activated mitophagy flux in human and mouse DMD models.
  • Fig. S4. UA induced mitophagy and regeneration in MuSCs from mdx mice.
  • Fig. S5. UA reduced muscle damage in mdx mice.
  • Fig. S6. UA ameliorated DMD symptoms in mdx and mdx/Utr−/− mice.
  • Legends for data files S1 and S2
  • References (6366)

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Individual subject-level data for main figures.
  • Data file S2 (Microsoft Excel format). Individual subject-level data for supplementary figures.