Supplementary Materials

The PDF file includes:

  • Fig. S1. Inhibition of P-gp retains calcein AM in proximal tubule cysts.
  • Fig. S2. Design and sensitivity of in-line metabolic sensors.
  • Fig. S3. CsA induces a shift to lipogenesis.
  • Fig. S4. Cisplatin induces a shift to lipogenesis.
  • Fig. S5. Glucose inhibition shifts the onset of cellular damage.
  • Fig. S6. Clinical validation in human patients segmented by sex.
  • Fig. S7. Expression of endoplasmic reticulum stress markers after drug exposure.
  • Table S1. Expression analysis of vascularized kidney spheroids.
  • Table S2. List of qRT-PCR primers.
  • Table S3. List of antibodies and probes.
  • Legend for data file S1
  • Legend for movie S1

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Raw data.
  • Movie S1 (.avi format). 3D reconstruction from LSM700 confocal Z-stack of a vascularized kidney spheroid labeled with AQP1.