Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Correlations between PlGF and carotid IMT.
  • Fig. S2. Association between plasma PlGF and severity of coronary disease in individuals with type 2 diabetes.
  • Fig. S3. Correlations between PlGF and risk factors.
  • Fig. S4. Associations of PlGF with diabetes, sex, and current smoking.
  • Fig. S5. Effect of PlGF siRNA on endothelial cell proliferation and expression of inflammatory genes.
  • Fig. S6. Effect of PlGF on endothelial cell proliferation and expression of inflammatory genes.
  • Fig. S7. PlGF gene expression in endothelial and SMCs.
  • Fig. S8. Effect of PlGF siRNA on SMC proliferation and expression of inflammatory genes.
  • Fig. S9. Effect of PlGF on SMC proliferation and expression of inflammatory genes.
  • Fig. S10. PlGF in plaque tissue and in plasma.
  • Fig. S11. Localization of PlGF in a human carotid plaque.
  • Fig. S12. Correlations between PlGF and other plaque components (I).
  • Fig. S13. Correlations between PlGF and other plaque components (II).
  • Fig. S14. PlGF and intra-plaque vessels in human coronary artery plaques.
  • Fig. S15. Flow chart of selection of study cohort.
  • Table S1. Partial correlation coefficients for associations of PlGF with carotid IMT.
  • Table S2. Partial correlation coefficients for associations of PlGF with sPECAM-1 and sTRAIL receptor-2.
  • Table S3. Cardiovascular event HRs and 95% CI for a 1 SD increase in plasma PlGF and sTRAIL receptor-2.
  • Table S4. Cardiovascular event HRs and 95% CI for a 1 SD increase in plasma PlGF and sTRAIL receptor-2.
  • Data file S1. STROBE checklist.
  • Reference (61)

[Download PDF]

Other Supplementary Material for this manuscript includes the following: