Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Purification of recombinant AIMP2.
  • Fig. S2. Biological consequences of AIMP2–α-synuclein interaction.
  • Fig. S3. Virally induced expression of α-synuclein and/or AIMP2 in vivo.
  • Fig. S4. α-Synuclein is required for AIMP2-stimulated Lewy-like inclusion formation.
  • Fig. S5. AIMP2 redistribution and α-synuclein aggregation in virally induced adult Parkin knockout mice.
  • Fig. S6. AIMP2 facilitates PFF-induced α-synuclein aggregation.
  • Fig. S7. AIMP2 contributes to 6-OHDA–induced α-synuclein aggregation.
  • Fig. S8. Genotyping of Aimp2 KO mice.
  • Table S1. Detailed information for postmortem human brain tissues used in this study.
  • Table S2. Detailed information for postmortem fixed temporal lobe sections from human PD brains used in this study (BBDP).
  • Legend for data file S1
  • References (5760)

[Download PDF]

Other Supplementary Material for this manuscript includes the following: