Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Cartilage-bone perfusion bioreactor design.
  • Fig. S2. Graft excision after 6 months of implantation.
  • Fig. S3. Morphology and composition of the engineered cartilage.
  • Fig. S4. Additional histological properties of the engineered cartilage.
  • Fig. S5. Creep compression of the engineered cartilage.
  • Fig. S6. Tribological properties of the engineered cartilage.
  • Fig. S7. RCU fixation during surgery.
  • Table S1. Animal ages at surgery and weights before surgery, after 3 months, and after 6 months.
  • Table S2. Complete blood counts after surgery, 3 months, and 6 months.
  • Table S3. Metabolic panels after surgery, 3 months, and 6 months.
  • Table S4. Published values on friction and modulus data for porcine TMJ.
  • Table S5. Experimental groups.
  • Legends for movies S1 to S5
  • Legend for data file S1
  • References (6276)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Computational simulated flow through RCU bioreactor.
  • Movie S2 (.mp4 format). Filling of ramus-condyle scaffold and bioreactor with medium.
  • Movie S3 (.mp4 format). Computational simulated flow through small construct bioreactor.
  • Movie S4 (.mp4 format). Filling of small scaffold and bioreactor with medium.
  • Movie S5 (.mp4 format). Cartilage friction testing.
  • Data file S1 (Microsoft Excel format). Primary data for cartilage thicknesses, biochemistry, creep compression, friction, and μCT.