Supplementary Materials

The PDF file includes:

  • Fig. S1. 1H NMR spectrum of HA-Cat.
  • Fig. S2. 1H NMR spectrum of HA-NCSN.
  • Fig. S3. UV-Vis spectra of HA-Cat mixed with a fivefold higher concentration of HA-NCSN.
  • Fig. S4. Mechanical comparison of HA-Cat-NCSN hydrogels and HA-Cat hydrogels.
  • Fig. S5. The physical properties of Ha-Cat-NCSN hydrogels.
  • Fig. S6. HA-Cat-NCSN hydrogels gelation induced by MT.
  • Fig. S7. Adhesion of HA-Cat-NCSN hydrogels on porcine gastric tissues in acidic wet environment.
  • Fig. S8. The gastric ulcers with or without hydrogel treatment in rodent models.
  • Fig. S9. ESD procedures in the stomach of the pig.
  • Fig. S10. Immune staining for iNOS on the stomach tissue harvested 48 hours after operation in pig.
  • Fig. S11. Schematic illustration of applying drugs to gastric ulcers in vivo.
  • Fig. S12. Biocompatibility assay of HA-Cat-NCSN.
  • Fig. S13. Schematic illustration of pepsin sequestration by hydrogels in an acidic environment.
  • Fig. S14. BSA release test of HA-Cat-NCSN hydrogels and MeHA hydrogels.
  • Legend for movie S1

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Adhesive and stable hydrogels formed on the acidic and wet procine gastric tissue in vitro.
  • Data file S1 (Microsoft Excel format). Individual subject-level data for quantitative analysis.