Supplementary Materials

The PDF file includes:

  • Materials and methods
  • Fig. S1. Fabrication of the highly flexible oCI substrates.
  • Fig. S2. Assembly and passivation of oCIs.
  • Fig. S3. Thermal simulation of an oCI.
  • Fig. S4. oCIs do not evoke potentials in littermate control rats lacking ChR2 or in ChR2-positive rats after euthanasia.
  • Fig. S5. Kanamycin-induced deafness in rats.
  • Fig. S6. Intracochlear temperature measurements in rats.
  • Fig. S7. Additivity of LEDs in eliciting oABRs in rats.
  • Fig. S8. Early postnatal transduction of gerbil and rat cochlea.
  • Fig. S9. oCIs do not cue avoidance behavior in naïve rats.
  • Table S1. Thermal simulation material properties.
  • Legend for data file S1
  • Legends for movies S1 to S3
  • References (4547)

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Raw data for graphs containing an n lower than 20.
  • Movie S1 (.mp4 format). Visualization of implanted cochlea by high-resolution x-ray tomography.
  • Movie S2 (.mp4 format). Visualization of oCI stimulation in the explanted rat cochlea.
  • Movie S3 (.mp4 format). Video of parts of a shuttle box session in a deaf, AAV-injected rat with the complete oCI system.