Supplementary Materials

The PDF file includes:

  • Material and Methods
  • Fig. S1. Identification of CRISPR-Cas9 potential off-target effects.
  • Fig. S2. Proof of pluripotency.
  • Fig. S3. Differentiation into all three germ layers.
  • Fig. S4. Karyogram analysis.
  • Fig. S5. Alterations in PMDS/InsG hiPSC–derived motoneurons and myogenic cells.
  • Fig. S6. Analysis of skeletal muscle features in Shank3Δ11(−/−) mice.
  • Fig. S7. Graphical illustration of the findings of this study.
  • Table S1. Genotype, gender, diagnosis, and clinical phenotype of donors for hiPSC lines.
  • Table S2. Muscle biopsy donors.
  • Legend for data file S1
  • Legends for movies S1 to S4
  • References (6875)

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Raw data.
  • Movie S1 (.avi format). Mice p0 to p1 BT whole mount category wave.
  • Movie S2 (.avi format). Mice p0 to p1 BT whole mount category crescent.
  • Movie S3 (.avi format). Mice p0 to p1 BT whole mount category oval.
  • Movie S4 (.avi format). Mice p0 to p1 BT whole mount category complex.