Supplementary Materials

The PDF file includes:

  • Fig. S1. Photographs of the iSAVE setup
  • Fig. S2. Differential tidal volume and PEEP delivery on the iSAVE using an open-circuit ventilator and test lungs
  • Fig. S3. Accommodation to changes in compliance of one test lung using the iSAVE and an open-circuit ventilator
  • Fig. S4. Ventilation at high lung resistances
  • Fig. S5. Ventilator alarm response to occlusion
  • Fig. S6. Adding a test lung to the circuit
  • Fig. S7. Cross-contamination validation using artificial lungs
  • Fig. S8. Individualized management of ventilation using iSAVE on a pig lung and a test lung
  • Fig. S9. Modification of sensing circuit for Hamilton G5 ventilator.
  • Fig. S10. Whistle ring designs for two types of common pressure release (PEEP) valves
  • Table S1. List of components required for the assembly of the iSAVE
  • Table S2. Mechanical components used in the iSAVE and their readily available medical industry equivalents
  • Table S3. Measurement of respiratory mechanics for iSAVE system using test lungs
  • Table S4. Blood electrolytes and chemistry during ventilation in pigs
  • Table S5. Stratification for patient matching

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