Supplementary Materials

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Characterization of artCP.
  • Fig. S2. Effects of artCP on endothelial cells in vitro.
  • Fig. S3. Effects of artCP on CPC differentiation in vitro.
  • Fig. S4. synCSC retention and biodistribution in rats.
  • Fig. S5. Immunogenicity of artCP in the post-MI rat heart.
  • Fig. S6. Rat heart dimensions measured by echocardiography.
  • Fig. S7. H&E staining of artCP and adjacent myocardium 21 days after transplantation in a rat.
  • Fig. S8. Treatment effects from empty, cryopreserved, or fresh artCP transplantation in rats.
  • Fig. S9. Heart morphometric analysis after patch transplantation in rats.
  • Fig. S10. Liver and kidney functions 21 days after artCP transplantation in rats.
  • Fig. S11. Percentage of pH3+ or Ki67+ cardiomyocytes in total cells 21 days after patch transplantation in rats.
  • Fig. S12. Staining of proliferation marker Aurora B after artCP or myoECM transplantation in rats.
  • Fig. S13. Analyses of myocardial proliferation and apoptosis 21 days after patch transplantation in rats.
  • Fig. S14. Effects of artCP therapy on angiomyogenesis in rats.
  • Fig. S15. Cardiac functional assessment of artCP therapy in a porcine MI model.
  • Fig. S16. Effects of artCP transplantation on liver and kidney functions in the porcine MI model.
  • Fig. S17. Immunogenicity analysis of artCP transplantation in the porcine MI model.
  • Table S1. myoECM average tension/stress versus strain.
  • Table S2. NHT average tension/stress versus strain.
  • Reference (69)

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