Supplementary Materials

The PDF file includes:

  • Fig. S1. Assessment of cytotoxicity of NHC in primary human epithelial cell cultures by qRT-PCR.
  • Fig. S2. High conservation of RdRp functional domains for SARS-CoV-2.
  • Fig. S3. Prophylactic EIDD-2801 reduces SARS-CoV replication and pathogenesis.
  • Fig. S4. Prophylactic EIDD-2801 reduces MERS-CoV replication and pathogenesis.
  • Table S1. Real-time PCR primer/probe sets for indicators of cellular apoptosis/toxicity.
  • Table S2. Primers used for MiSeq library prep and sequencing.

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Other Supplementary Material for this manuscript includes the following: