Supplementary Materials

The PDF file includes:

  • Fig. S1. Representative PD-L1 IHC staining within the prostate tumor microenvironment.
  • Fig. S2. Schema on identifying tumor-specific mutations and T cell responses to cancer neoantigens.
  • Fig. S3. Number of nonsynonymous mutations in primary and metastatic prostate cancers.
  • Fig. S4. Number of predicted neoantigens in primary versus metastatic prostate cancer using NetMHCpan.
  • Fig. S5. Number of nonsynonymous mutations in the prostate tumor tissues obtained from the favorable versus unfavorable cohorts.
  • Table S1. Baseline characteristics and laboratory values.
  • Table S2. Metastatic distribution of the patients at baseline.
  • Table S3. Prior systemic therapies.
  • Table S4. Selected irAEs.
  • Table S5. Identifying potential neoantigens with WES and RNA-seq.
  • Table S6. Comparison of identified and predicted neoantigens.

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Other Supplementary Material for this manuscript includes the following: