Supplementary Materials

The PDF file includes:

  • Fig. S1. GeneMANIA functional associations between top screen hits.
  • Fig. S2. Changes in GLUT1 and PDK1 expression in the presence of DUX4.
  • Fig. S3. Western blot protein quantification of single-gene knockouts.
  • Fig. S4. Effect of inhibitors on etoposide-induced cell death.
  • Fig. S5. Western blot time course of rapamycin dosing.
  • Fig. S6. DUX4 transcript expression with inhibitor treatment.
  • Fig. S7. FSHD biomarker expression in four patient lines with inhibitor treatment.
  • Table S1. Oligo sequences for single-gene knockout lines.
  • Table S2. Antibody concentrations.
  • Table S3. Primer sequences used for reverse transcription PCR.

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Other Supplementary Material for this manuscript includes the following: