Supplementary Materials

The PDF file includes:

• Fig. S1. FLNA expression is increased in cortices of patients with FCDII.
• Fig. S2. FLNA expression is increased in cytomegalic cortical neurons of patients with FCDII.
• Fig. S3. Original immunoblots for FLNA in human FCDII samples.
• Fig. S4. The quantity of FLNA is not correlated to the type of FCDII or age of seizure onset or epilepsy duration.
• Fig. S5. Knocking down FLNA does not affect the degree of S6 phosphorylation.
• Fig. S6. Delineation of layer 2/3 and layer 5 neurons using ER81 immunostaining.
• Fig. S7. Single-cell labeling for dendrite (Sholl) analysis.
• Fig. S8. Original immunoblots.
• Table S1. Information for patients with FCDII.
• Table S2. Information for control patients.
• Table S3. Summary of statistical tests.
• Table S4. Plasmids.
• Table S5. Primary and secondary antibodies.
• Legend for movie S1
• Legend for data file S1

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

• Movie S1 (.avi format). A Racine grade 4 to 5 seizure in a Rheb^CA-expressing mouse.
• Data file S1. Individual-level data for Figs. 1 to 6 and figs. S1, S4, and S5 (provided as separate Excel file).