Supplementary Materials

The PDF file includes:

  • Fig. S1. Preexposure of skin to topical IMQ increased host resistance to infection with SFV4.
  • Fig. S2. Type I IFN and ISG expression in skin and draining LN after IMQ application.
  • Fig. S3. Gene expression analysis of skin inoculation site-derived FACS isolated cells.
  • Fig. S4. IMQ-mediated protection against virus infection in keratinocytes is dependent on help from leukocytes.
  • Fig. S5. Topical IMQ prevents systemic dissemination of CHIKV to joint tissue remote from inoculation site.

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Other Supplementary Material for this manuscript includes the following: