Supplementary Materials

The PDF file includes:

• Materials and Methods
• Fig. S1. Association of TAU with the clinical pathology of diffuse gliomas.
• Fig. S2. Expression of TAU in PDX.
• Fig. S3. TAU correlates with the presence of IDH mutations.
• Fig. S4. The expression of MAPT is associated with the IDH mut DNA methylation phenotype.
• Fig. S5. Association of TAU function with the EGFR pathway in gliomas.
• Fig. S6. Association of TAU with the different GBM subtypes and the NF-κB–TAZ axis.
• Fig. S7. Vascular phenotypes associated with TAZ in gliomas.
• Fig. S8. Implication of the tumor-derived pericytes on the glioma vasculature and growth.
• Fig. S9 TAU negatively correlates with EGFR signaling and CD248 expression.
• Fig. S10. The vascular phenotype of gliomas is determined by the genetic status of EGFR and IDH and by the expression of TAU.
• Table S1. Human samples.
• Table S2. Paired human samples.
• Table S3. GBM cell lines.
• Table S4. Antibodies.
• Table S5. qRT-PCR primers.
• Table S6. Sequencing primers.
• Legend for data file S1

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Other Supplementary Material for this manuscript includes the following:

• Data file S1. Raw data (provided as separate Excel file).