Supplementary Materials

The PDF file includes:

  • Fig. S1. Experimental design and characterization of acute and chronic pancreatitis mouse models.
  • Fig. S2. Experimental design, histology, and gene expression data for FGF21 therapy experiments in three different models of pancreatitis.
  • Fig. S3. Atf3 and Atf4 expression in pancreatitis mouse models and ATF3 and ATF4 ChIP experimental controls.
  • Fig. S4. ATF3 and ATF4 expression in 266-6 cells.
  • Fig. S5. Model of FGF21’s protective role in pancreatitis.
  • Table S1. qPCR primer sequences.
  • Table S2. Primary antibody list.
  • Table S3. ChIP-qPCR primer sequences.

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Human pancreas tissue donor information.
  • Data file S2 (Microsoft Excel format). Raw numbers for each data point in each graph from the study.