Supplementary Materials

The PDF file includes:

  • Material and Methods
  • Fig. S1. Oral mucosa pathology assessment.
  • Fig. S2. CD4 TRM phenotype and localization in human oral mucosa.
  • Fig. S3. T cells as a percentage of total nucleated cells in healthy oral mucosal tissue.
  • Fig. S4. CD8 T cell and CD4 T cell changes with inflammation in human oral mucosa.
  • Fig. S5. Network analysis and GSEA for bulk RNA-seq of CD4 T cells from blood and oral mucosa samples.
  • Fig. S6. scRNA-seq.
  • Fig. S7. CD4 T cell functional potential.
  • Fig. S8. Impact of the CCR5 antagonist Maraviroc on CD4 T cell subsets in human rectal mucosa.
  • References (6165)

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). List of donors used in this study.
  • Table S2 (Microsoft Excel format). DE gene list comparing CCR5+ CD4 T cells from human blood and oral mucosa from bulk RNA-seq.
  • Table S3 (Microsoft Excel format). List of TH17-associated genes used for scRNA-seq analysis.
  • Table S4 (Microsoft Excel format). List of commercially available antibodies used for IF experiments.
  • Table S5 (Microsoft Excel format). List of DE genes between CCR5+ (fold change up) and CCR5 (fold change down) cells from scRNA-seq in human oral mucosa.
  • Data file S1 (Microsoft Excel format). Primary data.