Supplementary Materials

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Laboratory-scale co-encapsulation of micronutrients.
  • Fig. S2. Vitamin B12 release as a function of pH.
  • Fig. S3. HA-BMC MP electron micrograph after 2 hours in boiling water.
  • Fig. S4. Spectral fingerprinting of DiR-loaded MPs.
  • Fig. S5. Release, electron micrographs, and time history of color change for 3.19 and 18.29% Fe-HA-BMC MPs.
  • Fig. S6. Evaluation of iron absorption from 3.19% Fe-HA-BMC MPs in humans when co-administered with VitA-BMC MPs and free folic acid.
  • Fig. S7. Comparison of iron absorption from 3.19% Fe-HA-BMC MPs with each MP constituent both individually and in combination.
  • Table S1. Polymers evaluated as potential MP matrix materials.
  • Table S2. Formulation parameters and loadings for laboratory-scale MPs.
  • Table S3. Subject characteristics of human studies 1 and 2.
  • Table S4. Process design formulation parameters and loadings for MPs used in the second human study.
  • Table S5. Quality control tests for MPs used in both human studies.
  • References (6592)

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