Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Agarose mold of the human brainstem.
  • Fig. S2. Simulation of CN electrical stimulation.
  • Fig. S3. Process flow for microstructured PI/Pt/PI multilayer.
  • Fig. S4. Electron microscopy of microstructured multilayers of PI/Pt/PI.
  • Fig. S5. Geometric construction of the Y-shaped pattern.
  • Fig. S6. Equivalent electrical circuit of microstructured electrical tracks.
  • Fig. S7. Resistance of microstructured PI/Pt/PI tracks.
  • Fig. S8. Electrical redundancy of tracks with Y-shaped micropatterns.
  • Fig. S9. Critical dimension of the Y-shaped pattern.
  • Fig. S10. Smallest theoretical track width of a microstructured interconnect.
  • Fig. S11. Smallest practical track width of a microstructured interconnect.
  • Fig. S12. Failure mechanisms of nonstructured PI/Pt/PI tracks compared to microstructured PI/Pt/PI tracks.
  • Fig. S13. Electromechanical properties of microstructured tracks of varying width.
  • Fig. S14. Apparent elastic modulus of microstructured tracks embedded in PDMS.
  • Fig. S15. Conformability of membranes on wet cylinders.
  • Fig. S16. Dimension comparison of the clinical and soft ABI.
  • Fig. S17. Curvature measurements of the DCN surface from human histological slices.
  • Fig. S18. Swelling over time of the hydrosoluble guide.
  • Fig. S19. MRI comparison of the clinical and soft ABI in a cadaveric brain.
  • Fig. S20. Electrical and dimensional layout of the mouse ABI electrode array.
  • Fig. S21. Schematics and photographs of the surgical procedure of the mouse ABI electrode array implantation.
  • Fig. S22. Examples of aABRs.
  • Fig. S23. Comparison of neural recordings with a control not-connected pin.
  • Fig. S24. PSTHs evoked by monopolar stimulation.
  • Table S1. Parameters of electrical conductivity used for simulation.
  • Table S2. Coordinates of the arcs defining the Y-shaped motifs.
  • Table S3. Summary of results for the optimization study.
  • Legends for movies S1 to S3
  • References (4952)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1. Surgical approach using a rigid clinical ABI in a cadaveric specimen.
  • Movie S2. Surgical approach using a soft ABI in a cadaveric specimen.
  • Movie S3. Surgical approach using a soft ABI with temporary hydrosoluble guide in a cadaveric specimen.