Supplementary Materials

The PDF file includes:

• Materials and Methods
• Fig. S1. Study design.
• Fig. S2. Pathological HFOs present isolated high-frequency component and generate compact subclusters in the time domain.
• Fig. S3. Comparison between HFB activations in epileptic and in nonepileptic sites.
• Fig. S4. Temporal and spectral profiles of HFO and HFB signals in all subjects.
• Fig. S5. Feature distribution of HFBs and HFOs in all subjects.
• Fig. S6. ROC curves for the SVM classifier.
• Fig. S7. Concatenated power time series showing spontaneous HFOs and stimulus-locked HFBs during cognitive task.
• Fig. S8. Signal properties of HFOs during behavioral task.
• Fig. S9. Comparison between disruptive and nondisruptive HFOs in all subjects.
• Fig. S10. Electrophysiological effect of slow spikes during task 2.
• Legend for data file S1
• References (48–52)

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Other Supplementary Material for this manuscript includes the following:

• Data file S1 (Microsoft Excel format). Raw data.