Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. μOCT reflectance intensity reflects viscosity in expectorated sputum samples.
  • Fig. S2. Elevated mucus optical reflectance intensity in subjects with CF.
  • Fig. S3. Representative in vitro μOCT images of transepithelial neutrophil migration.
  • Fig. S4. Granulocytes in swine mucus.
  • Fig. S5. Scatter plots showing inter- and intra-observer reliability.
  • Fig. S6. An illustration of extraction of CBF after motion stabilization.
  • Table S1. Demographics and CF characteristics of study participants.
  • Table S2. Summary of univariate analysis.
  • Table S3. Summary of multivariate analysis.
  • Legends for movies S1 and S2
  • References (5256)

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). MCT in a healthy control subject.
  • Movie S2 (.avi format). Epithelial injury and mucostasis in a subject with CF.