Supplementary Materials

The PDF file includes:

  • Computer code for statistical tests
  • Fig. S1. Pixel-wise heatmap of MRI biexponential T2 fit results.
  • Fig. S2. Histogram of MRI pixel-wise T2 relaxation time values in muscular and subcutaneous tissue at baseline.
  • Fig. S3. Histogram of MRI pixel-wise T2 relaxation time values in muscular tissue.
  • Fig. S4. Histogram of MRI pixel-wise T2 relaxation time values in subcutaneous tissue.
  • Fig. S5. Histogram of MRI pixel-wise RAlong values in muscular tissue.
  • Fig. S6. Histogram of MRI pixel-wise RAlong values in subcutaneous tissue.
  • Fig. S7. CDFs of MRI pixel-wise RAlong values in muscular tissue.
  • Fig. S8. T2 decays of phantoms measured on MRI and NMR sensor.
  • Fig. S9. T2 results of phantoms measured on MRI and NMR sensor.
  • Fig. S10. Quantitative NMR relaxometry findings at different fluid states.
  • Fig. S11. Pixels deleted by the MRI pixel-wise fitting criteria.
  • Fig. S12. Bo magnetic field map of the NMR sensor.
  • Fig. S13. NMR sensor T2 decay signal from a representative HC and HD participant.
  • Legend for table S1
  • Table S2. F test comparison of multiexponential fits for pixel-wise MRI data.
  • Table S3. Summary of change in pixel-wise MRI values within ROIs.
  • Table S4. Summary of quantile regression results for MRI pixel-wise RAlong values from the muscle ROI.
  • Table S5. Summary of MRI RAlong values for muscle (whole ROI average).
  • Table S6. Comparison of specifications of the NMR sensor with those of a traditional MRI scanner.
  • Table S7. Summary of phantom T2 relaxation time results for MRI and NMR sensor.
  • Table S8. Summary of RAb values from NMR sensor.
  • Table S9. Summary of RAlong values from MRI small voxel: Anterior 1 with subcutaneous and muscle.
  • Table S10. Summary of RAlong values from MRI small voxel: Anterior 2 with muscle only.
  • Table S11. Summary of RAlong values from MRI small voxel: Lateral 1 with subcutaneous and muscle.
  • Table S12. Summary of RAlong values from MRI small voxel: Lateral 2 with muscle only.
  • Table S13. Summary of whole-body Re BI values.
  • Table S14. Summary of whole-body Rinf BI results.
  • Table S15. Summary of leg segmental Re BI results.
  • Table S16. Summary of leg segmental Rinf BI results.
  • Table S17. Change in T2 relaxation time of phantom measured with each human NMR sensor measurement.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Individual-level demographics of the study population.