Supplementary Materials

The PDF file includes:

  • Fig. S1. Classification of patients into management groups.
  • Fig. S2. Cyst fluid VEGF-A.
  • Fig. S3. Cyst fluid CEA.
  • Fig. S4. Association between aneuploidy and high-grade dysplasia or cancer.
  • Legends for tables S1 to S9

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Clinical, imaging, molecular, and pathological data for all 862 patients with surgically resected pancreatic cysts.
  • Table S2 (Microsoft Excel format). Genetic characteristics of the IPMNs based on histological subtype.
  • Table S3 (Microsoft Excel format). CompCyst and the preoperative clinical diagnosis and management recommendations.
  • Table S4 (Microsoft Excel format). Performance of the three-step approach to classify cysts into management groups.
  • Table S5 (Microsoft Excel format). CompCyst and preoperative clinical management recommendations compared with surgical pathology.
  • Table S6 (Microsoft Excel format). Identification of cyst type: comparison of CompCyst, the preoperative clinical diagnosis, and surgical pathology.
  • Table S7 (Microsoft Excel format). Primer sequences used in Safe-SeqS.
  • Table S8 (Microsoft Excel format). Primer sequences used in Safe-SeqS for loss of heterozygosity.
  • Table S9 (Microsoft Excel format). Frequency of molecular features associated with different grades of dysplasia in mucin-producing cysts.