Supplementary Materials

The PDF file includes:

  • Methods
  • Fig S1. Rat GluN1-GluN2A holoprotein and disease induction.
  • Fig S2. Neuropathological assessment at 3 weeks after immunization.
  • Fig S3. IgG immunolabeling at 3 weeks after immunization.
  • Fig S4. GluN1 subunit–specific immunocytochemistry in HEK cells.
  • Fig S5. IgG deposits in CNS at 6 weeks after immunization.
  • Fig S6. Response of B cell mutant mice to proteoliposome treatment.
  • Legend for table S1
  • Legends for movies S1 to S5

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). Individual values for all analyses with n < 20.
  • Movie S1 (.mp4 format). Representative liposome-treated control mouse in home cage.
  • Movie S2 (.mp4 format). Proteoliposome-treated mouse with locomotor hyperactivity.
  • Movie S3 (.mp4 format). Proteoliposome-treated mouse with aberrant circling.
  • Movie S4 (.mp4 format). Proteoliposome-treated mouse during a clinical seizure.
  • Movie S5 (.mp4 format). Proteoliposome-treated mouse with prominent hunched back and lethargy.