Supplementary Materials

The PDF file includes:

  • Methods
  • Fig. S1. In vitro glucose–induced insulin secretion by PTP1B−/− and PTP1B+/+ mouse islets.
  • Fig. S2. Characterization of PTP1B−/− and PTP1B+/+ mouse islets after 7 days in culture.
  • Fig. S3. Immunolocalization of VEGF-A in PTP1B−/− and PTP1B+/+ mouse islets.
  • Fig. S4. Characterization of human islet preparations.
  • Fig. S5. Assessment of the uptake of siRNA by human islets.
  • Fig. S6. Proposed model for the effect of PTP1B inhibition on islet graft vascularization.
  • Table S1. Human islet donor information.
  • References (64, 65)

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Other Supplementary Material for this manuscript includes the following: