Supplementary Materials

This PDF file includes:

  • Fig. S1. Subcutaneous pump placement effect on survival.
  • Fig. S2. Blood pressure effect in Fbn1mgR/mgR mice.
  • Fig. S3. OR mRNA expression in the proximal ascending aorta.
  • Fig. S4. Blood pressure effect in Fbn1mgR/mgR mice.
  • Table S1. Average aortic root and ascending aortic growth over the 7-week period spanning pregnancy and lactation in untreated mice.
  • Table S2. Average aortic root and ascending aortic growth over the 7-week period spanning pregnancy and lactation in treated mice.
  • Table S3. Effect of OTA treatment on the average systolic and diastolic blood pressure.
  • Table S4. Average OR expression in the aorta.
  • Table S5. Effect of hydralazine or propranolol on the average systolic and diastolic blood pressure.
  • Table S6. Average ERK1/2 phosphorylation in untreated mice.
  • Table S7. Average ERK1/2 phosphorylation in treated mice.
  • Table S8. Effect of trametinib on average systolic and diastolic blood pressure.
  • Table S9. Average ERK1/2 phosphorylation in trametinib-treated mice.

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