Supplementary Materials

The PDF file includes:

  • Fig. S1. Temperature testing setup.
  • Fig. S2. Evolution of temperature measured while administering warm water.
  • Fig. S3. Flower-like prototype.
  • Fig. S4. Fabrication and assembly of the flower-like prototype.
  • Fig. S5. Heat treatment of shape-memory nitinol.
  • Fig. S6. Mechanical characterization of the flower-like prototype.
  • Fig. S7. Fabrication of degradable millineedles.
  • Fig. S8. Reconfigurable mechanical metamaterial as a macrostructure dosage form.
  • Fig. S9. Drug stability and in vitro release of drug-loaded arms.
  • Fig. S10. Mechanical characterization of the drug-loaded arms by three-point bending tests.
  • Fig. S11. Mechanical characterization of the interfaces between the polymer arms and elastic hinges by uniaxial tension tests.
  • Legends for movies S1 and S2

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). In vivo deployment, closure, and passage of the flower-like prototype in the esophagus.
  • Movie S2 (.mp4 format). In vivo deployment, closure, and passage of the flower-like prototype in the esophagus in the reverse direction.
  • Data file S1. Primary data (provided as an Excel file).