Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Survival curves for CD36 and other genes encoding proteins regulating fatty acid uptake.
  • Fig. S2. Fatty acid uptake in prostate cancer cell lines.
  • Fig. S3. shRNA knockdown of CD36 in PC3 and LNCaP cells.
  • Fig. S4. Mouse phenotyping by flow cytometric analysis.
  • Fig. S5. Phenotype of WT.Cd36−/− mice.
  • Fig. S6. Assessment of metabolism and cancer pathology in Pten−/−.Cd36−/− mice fed a high-fat diet for 6 weeks.
  • Fig. S7. Schematic depicting the changes in Pten−/−-induced lipid metabolism that link the production of oncogenic lipids to prostate cancer progression.
  • Fig. S8. Linking cPLA2α inhibition to the antitumorigenic effects of Cd36 deletion.
  • Fig. S9. Systemic effects of CD36 mAb treatment in mice.
  • Table S1. Patient characteristics of specimens used for metabolism studies.
  • References (5878)

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Other Supplementary Material for this manuscript includes the following: