Supplementary Materials

The PDF file includes:

  • Fig. S1. The expression of HDAC3 in mouse uteri during early pregnancy and in all phases of the estrous cycle.
  • Fig. S2. Normal ovarian histology and serum progesterone and estrogen in Hdac3d/d mice.
  • Fig. S3. Decidualization defect in Hdac3d/d mice after artificially induced decidualization.
  • Fig. S4. Increased collagen in the uteri of Hdac3d/d mice.
  • Fig. S5. Motif analysis on HDAC3 interval sequences.
  • Fig. S6. Identification of Hdac3 target genes in the mouse uterus.
  • Fig. S7. Recruitment of HDAC3 on COL1A1 and COL1A2 genes.
  • Fig. S8. Overexpression of collagen in the uteri of Hdac3d/d mice.
  • Fig. S9. Immunohistochemical analysis of COL1 in the uteri of Hdac3d/d mice.
  • Table S1. Infertility in Hdac3d/d female mice.
  • Table S2. Normal ovulation and fertilization in Hdac3d/d female mice.
  • Table S3. Dysregulation of atherosclerosis and fibrosis pathways in the uteri of Hdac3d/d mice.
  • Table S4. List of primers used in RT-qPCR analysis.

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Other Supplementary Material for this manuscript includes the following:

  • Table S5. Raw data (provided as an Excel file).