Supplementary Materials

This PDF file includes:

  • Methods
  • Materials and Methods
  • Fig. S1. Causal relationship between transcription factors and miRNAs.
  • Fig. S2. Differences in cell type proportions between cases (BD and SCZ) and controls.
  • Fig. S3. Immunofluorescence staining of human NPCs.
  • Fig. S4. RT-qPCR analysis of POU3F2 knockdown efficiency.
  • Fig. S5. Distribution of eigengene values in daM.
  • Table S1. Demographic and clinical information for discovery SMRI data.
  • Table S2. Demographic and clinical information for replicated BrainGVEX data.
  • Table S3. Overlap of genes in the daM and genes with rare variants.
  • Table S4. Transcription factor expression associated with disease in SMRI and BrainGVEX data.
  • Table S5. Transcription factor expression correlations in BrainGVEX data.
  • Table S6. OCA (LEO.NB.OCA) and CPA (LEO.NB.CPA) scores for six transcription factors and one miRNA.
  • Table S7. Sequences of RT-qPCR primers and siRNA.
  • Table S8. Top 50 connected genes in the daM, miRNAs, transcription factors, and their WGCNA parameters.
  • Table S9. POU3F2 and its putative targets in daM.
  • References (4664)

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