Supplementary Materials

The PDF file includes:

  • Methods
  • Fig. S1. BRAF inhibitors enhance T-VEC cell killing in BRAF-mutant melanoma cell lines.
  • Fig. S2. LumaCyte laser flow cytometry analysis.
  • Fig. S3. T-VEC and MEKi–induced apoptosis.
  • Fig. S4. Characterization of murine D4M3A cells.
  • Fig. S5. Validation of immune cell depletion.
  • Fig. S6. Time course analysis of tumor-infiltrating CD8+ T cells during mT-VEC treatment.
  • Fig. S7. Analysis of CD8+ T cells from spleen during mT-VEC + MEKi treatment.
  • Fig. S8. Characterization of D4M3A tumor cells in Batf3 knockout mice.
  • Fig. S9. NanoString gene expression heat maps for all genes profiled and by gene function.
  • Fig. S10. MFI expression of PD-1 expression and frequency of PD-1+ cells.
  • Fig. S11. Individual tumor growth curves of BALB/c mice bearing CT26 tumors.
  • Table S1. Antibodies.
  • Table S2. Chemicals.
  • Table S3. Commercial assays.
  • Table S4. Experimental cell lines.
  • Table S5. Experimental models.
  • Legend for table S6

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Other Supplementary Material for this manuscript includes the following:

  • Table S6 (Microsoft Excel format). Tumor area from mouse studies.
  • Data file S1 (.txt format). Gene expression raw data.