Supplementary Materials

This PDF file includes:

  • Fig. S1. DKK3 expression and silencing.
  • Fig. S2. DKK3 expression and function in HPSCs and PDAC cells.
  • Fig. S3. DKK3 expression in syngeneic models of PDAC.
  • Fig. S4. DKK3 depletion in the P48-Cre; KrasLSL-G12D;Trp53fl/+ model of PDAC.
  • Fig. S5. DKK3 expression in an autochthonous model of PDAC and effects of DKK3 mAb on cell surface binding of DKK3 and an orthotopic model.
  • Fig. S6. DKK3 expression in mouse PSCs and effects of treatment with DKK3 mAb on survival.

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