Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Outline of inclusion criteria and experimental prioritization of cord blood samples.
  • Fig. S2. Fetal effector memory CD4+ T cell frequencies are altered by parasites in the placenta but not by maternal gravidity or IPT arm.
  • Fig. S3. Fetal effector and memory CD8+ T cell subsets do not differ with PM exposure.
  • Fig. S4. Cord blood CD4+ T cell responses are fetal in origin.
  • Fig. S5. Cord blood CD4+ T cell responses are transcriptionally heterogeneous.
  • Fig. S6. Cytokine production by cord blood CD4+ and CD8+ T cells.
  • Fig. S7. Characterization of cord blood CD4+ and CD8+ T cell proliferation in response to malaria antigens.
  • Fig. S8. Gating strategy for CD4+ and CD8+ T cell populations.
  • Table S1. CD4+ T cell proliferation in response to malaria antigens is associated with protection from childhood malaria with adjustment for maternal malaria exposure.
  • Table S2. Details of clinical cohort.
  • Table S3. Details of flow cytometric antibodies.

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Other Supplementary Material for this manuscript includes the following:

  • Table S4 (Microsoft Excel format). Primary data.