Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Exome and genome mutation signature profiles and evidence of strand bias support identification of signatures 7 and 5.
  • Fig. S2. Signature 5 correlates with age in RDEB SCC.
  • Fig. S3. RNA sequencing analysis of RDEB SCC tumors.
  • Fig. S4. APOBEC gene expression in HNSCC subtypes and UV SCC.
  • Fig. S5. APOBEC3A mutation motifs are enriched in RDEB SCC.
  • Fig. S6. Histology of tumors used for M-WES.
  • References (4355)

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). RDEB SCC tumor sample details.
  • Table S2 (Microsoft Excel format). Somatic mutations identified across 27 RDEB SCC tumors.
  • Table S3 (Microsoft Excel format). MuSiC output analysis of 27 RDEB SCC tumors.
  • Table S4 (Microsoft Excel format). MutSigCV output analysis of 27 RDEB SCC tumors.
  • Table S5 (Microsoft Excel format). Copy number variations identified across 27 RDEB SCC tumors.

[Download Tables S1 to S5]