Supplementary Materials

The PDF file includes:

  • Materials and Methods
  • Fig. S1. Representative IHC images.
  • Fig. S2. Correlations of MHC class I IHC scores with β2M IHC scores and HLA transcripts.
  • Fig. S3. Study schemas for the CheckMate 064 and CheckMate 069 trials.
  • Fig. S4. Comparison of MHC class I and MHC class II expression in paired baseline and week 13 biopsy samples from CheckMate 064.
  • Legend for table S1
  • Table S2. Best overall response of PD and non-PD according to optimally defined biomarker thresholds.
  • Legend for table S3
  • Table S4. Genes used in the published IFN-γ signature.
  • Table S5. Genes used in the NK cell and γδ T cell gene sets.
  • References (5159)

[Download PDF]

Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). CheckMate 064 MHC class I and MHC class II IHC.
  • Table S3 (Microsoft Excel format). CheckMate 069 MHC class I and MHC class II IHC.

[Download Tables S1 and S3]