Supplementary Materials

Supplementary Material for:

The ERBB network facilitates KRAS-driven lung tumorigenesis

Björn Kruspig, Tiziana Monteverde, Sarah Neidler, Andreas Hock, Emma Kerr, Colin Nixon, William Clark, Ann Hedley, Sarah Laing, Seth B. Coffelt, John Le Quesne, Craig Dick, Karen H. Vousden, Carla P. Martins, Daniel J. Murphy*

*Corresponding author. Email: daniel.murphy{at}

Published 20 June 2018, Sci. Transl. Med. 10, eaao2565 (2018)
DOI: 10.1126/scitranslmed.aao2565

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Characterization of KM lung tumors.
  • Fig. S2. Comparison of KM phenotype induced by Ad-CMV-CRE and Ad-SPC-CRE.
  • Fig. S3. Genomic alterations and expression of ERBB network genes in human KRAS-mutant LuAd.
  • Fig. S4. Sensitivity of KRAS-mutant cell lines to ERBB blockade.
  • Fig. S5. Longitudinal in vivo imaging of nascent lung tumors.
  • Table S1. Summary of Metacore GeneGO pathway analysis.
  • References (4247)

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