Supplementary Materials

Supplementary Material for:

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys

Peter Abbink, Rafael A. Larocca, Kittipos Visitsunthorn, Michael Boyd, Rafael A. De La Barrera, Gregory D. Gromowski, Marinela Kirilova, Rebecca Peterson, Zhenfeng Li, Ovini Nanayakkara, Ramya Nityanandam, Noe B. Mercado, Erica N. Borducchi, Abishek Chandrashekar, David Jetton, Shanell Mojta, Priya Gandhi, Jake LeSuer, Shreeya Khatiwada, Mark G. Lewis, Kayvon Modjarrad, Richard G. Jarman, Kenneth H. Eckels, Stephen J. Thomas, Nelson L. Michael, Dan H. Barouch*

*Corresponding author. Email: dbarouch{at}bidmc.harvard.edu

Published 13 December 2017, Sci. Transl. Med. 9, eaao4163 (2017)
DOI: 10.1126/scitranslmed.aao4163

This PDF file includes:

  • Fig. S1. Immune correlates analysis in mice.
  • Fig. S2. Cellular immune responses in the ZIKV PIV vaccine study.
  • Fig. S3. Cellular immune responses in the ZIKV DNA-M-Env and RhAd52-MEnv vaccine study.
  • Fig. S4. Cross-strain neutralization of a panel of ZIKV strains.
  • Fig. S5. Antibody-dependent enhancement assays in the ZIKV PIV vaccine study.
  • Fig. S6. Antibody-dependent enhancement assays in the ZIKV DNA-M-Env and RhAd52-M-Env vaccine study after challenge.
  • Fig. S7. MN50 titers in the ZIKV PIV vaccine study after challenge.
  • Fig. S8. MN50 titers in the ZIKV DNA-M-Env and RhAd52-M-Env vaccine study after challenge.
  • Fig. S9. Cellular immune responses in the ZIKV DNA-M-Env and RhAd52-MEnv vaccine study after challenge.
  • Fig. S10. Immune correlates analysis in vaccinated and sham control rhesus monkeys.
  • Fig. S11. Adoptive transfer studies of rhesus monkey IgG in mice.

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Other Supplementary Material for this manuscript includes the following: