Supplementary Materials

Supplementary Material for:

Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia

Chatmanee Lertudomphonwanit, Reena Mourya, Lin Fei, Yue Zhang, Sridevi Gutta, Li Yang, Kevin E. Bove, Pranavkumar Shivakumar, Jorge A. Bezerra*

*Corresponding author. Email: jorge.bezerra{at}

Published 22 November 2017, Sci. Transl. Med. 9, eaan8462 (2017)
DOI: 10.1126/scitranslmed.aan8462

This PDF file includes:

  • Fig. S1. GGT mRNA expression.
  • Fig. S2. Relationship between MMP-7 and hepatic fibrosis at the time of diagnosis of BA.
  • Fig. S3. Murine Ggt1 mRNA expression.
  • Table S2. List of 76 serum proteins differentially expressed in BA and IHC.
  • Table S3. Prediction of BA by MMP-7 in validation cohort #2.
  • Table S4. Primer sequences and PCR product sizes for mouse Mmp-7-, Ggt1-, Th1-, Tnfa-, and IL8-related genes.

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Other Supplementary Material for this manuscript includes the following:

  • Table S1. Protein results from SOMAscan (provided as an Excel file).

[Download Table S1]