Supplementary Materials

Supplementary Material for:

Integrated genomic and interfacility patient-transfer data reveal the transmission pathways of multidrug-resistant Klebsiella pneumoniae in a regional outbreak

Evan S. Snitkin,* Sarah Won, Ali Pirani, Zena Lapp, Robert A. Weinstein, Karen Lolans, Mary K. Hayden*

*Corresponding author. Email: esnitkin{at}umich.edu (E.S.S.); mhayden{at}rush.edu (M.K.H.)

Published 22 November 2017, Sci. Transl. Med. 9, eaan0093 (2017)
DOI: 10.1126/scitranslmed.aan0093

This PDF file includes:

  • Fig. S1. Epidemic curve of outbreak across regional health care facilities.
  • Fig. S2. Maximum likelihood tree of outbreak isolates.
  • Fig. S3. Distribution of overlaps between genomic and patient-sharing networks for randomized data.
  • Fig. S4. Ancestral facility reconstruction for collection including surveillance isolates from NH-B and LTACH-A.
  • Fig. S5. Variants identified among outbreak isolates.
  • Fig. S6. Correlation between date of isolation and genetic distance from common ancestor.
  • Fig. S7. Maximum likelihood ancestral reconstruction of outbreak isolates.
  • Table S1. Patient-transfer events associated with genomically inferred interfacility transmissions.
  • Table S2. Summary of whole-genome sequencing in the current study.

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