Supplementary Materials
Supplementary Material for:
Staphylococcus aureus and Staphylococcus epidermidis strain diversity underlying pediatric atopic dermatitis
Allyson L. Byrd, Clay Deming, Sara K. B. Cassidy, Oliver J. Harrison, Weng-Ian Ng, Sean Conlan, Yasmine Belkaid, Julia A. Segre,* Heidi H. Kong*
*Corresponding author. Email: jsegre{at}mail.nih.gov (J.A.S.); konghe{at}mail.nih.gov (H.H.K.)
Published 5 July 2017, Sci. Transl. Med. 9, eaal4651 (2017)
DOI: 10.1126/scitranslmed.aal4651
This PDF file includes:
- Materials and Methods
- Fig. S1. Seven sites sampled bilaterally on pediatric AD patients and control children.
- Fig. S2. Full multikingdom taxonomic classifications for AD patients and controls.
- Fig. S3. Full Malassezia species classifications for AD patients and controls.
- Fig. S4. Full eukaryotic virus classifications for AD patients and controls.
- Fig. S5. Full bacterial taxonomic classifications for AD patients and controls.
- Fig. S6. Relative abundance of staphylococcal species in relation to total bacterial population for all sites in AD patients and controls.
- Fig. S7. Correlation of various staphylococcal species mean relative abundance and objective SCORAD for all sites of patients.
- Fig. S8. Relative abundance of staphylococcal species for all sites in AD patients and controls.
- Fig. S9. S. aureus clades for AD patients and controls.
- Fig. S10. S. epidermidis clades for AD patients and controls.
- Fig. S11. Histologic and cutaneous innate immune cell responses with AD isolate association in a murine model.
- Fig. S12. CD45+ cutaneous immune responses with AD isolate association in a murine model.
- Table S1. Subject Tanner stage and disease severity for samples used in this study.
- Table S2. Clinical metadata for the subjects in this study.
- References (69–75)
Other Supplementary Material for this manuscript includes the following:
- Table S3 (Microsoft Excel format). Metadata table for all samples in this study.
- Table S4 (Microsoft Excel format). Multikingdom relative abundances (coverage, >1% of the reference genome).
- Table S5 (Microsoft Excel format). Malassezia relative abundance.
- Table S6 (Microsoft Excel format). Bacteria relative abundances (coverage, >1% of the reference genome).
- Table S7 (Microsoft Excel format). Staphylococcus species relative abundances.
- Table S8 (Microsoft Excel format). S. aureus clade abundances.
- Table S9 (Microsoft Excel format). S. aureus pangenome analysis for isolates cultured and sequenced in this study.
- Table S10 (Microsoft Excel format). S. epidermidis strain relative abundances.