Supplementary Materials

Supplementary Material for:

Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy

Katherine S. Yang, Hyungsoon Im, Seonki Hong, Ilaria Pergolini, Andres Fernandez del Castillo, Rui Wang, Susan Clardy, Chen-Han Huang, Craig Pille, Soldano Ferrone, Robert Yang, Cesar M. Castro, Hakho Lee, Carlos Fernandez del Castillo, Ralph Weissleder*

*Corresponding author. Email: rweissleder{at}

Published 24 May 2017, Sci. Transl. Med. 9, eaal3226 (2017)
DOI: 10.1126/scitranslmed.aal3226

This PDF file includes:

  • Fig. S1. NPS setup.
  • Fig. S2. Comparison of PDAC and EV markers on cells and EVs.
  • Fig. S3. EV markers in a training cohort.
  • Fig. S4. Comparison of EV counts with conventional clinical metrics.
  • Fig. S5. NPS signal from validation cohort tEVs.
  • Fig. S6. EV counts for patients with different types of pancreatic diseases.
  • Fig. S7. Comparison of the PDACEV signature and SSTR2 in different patient cohorts.
  • Table S1. Antibodies used in flow cytometry and NPS.
  • References (40, 41)

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