Supplementary Materials

Supplementary Material for:

Nociceptive brain activity as a measure of analgesic efficacy in infants

Caroline Hartley, Eugene P. Duff, Gabrielle Green, Gabriela Schmidt Mellado, Alan Worley, Richard Rogers, Rebeccah Slater*

*Corresponding author. Email: rebeccah.slater{at}

Published 3 May 2017, Sci. Transl. Med. 9, eaah6122 (2017)
DOI: 10.1126/scitranslmed.aah6122

This PDF file includes:

  • Fig. S1. Comparison of the noxious brain activity evoked by the clinical and experimental stimulus modalities.
  • Fig. S2. Evoked activity in individual infants demonstrating sensitivity to analgesic modulation.
  • Fig. S3. ROC curve.
  • Table S1. Identification of the stimulus modalities applied to each infant in study 1.

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (.mat format). Template of nociceptive brain activity in infants (provided as a separate file).
  • Data file S2 (.m format). MATLAB code to project the template onto new EEG data (provided as a separate file).

[Download Data files S1 and S2]