Supplementary Materials

Supplementary Material for:

A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice

Tyson R. Chiaro, Ray Soto, W. Zac Stephens, Jason L. Kubinak, Charisse Petersen, Lasha Gogokhia, Rickesha Bell, Julio C. Delgado, James Cox, Warren Voth, Jessica Brown, David J. Stillman, Ryan M. O'Connell, Anne E. Tebo, June L. Round*

*Corresponding author. Email: june.round{at}

Published 8 March 2017, Sci. Transl. Med. 9, eaaf9044 (2017)
DOI: 10.1126/scitranslmed.aaf9044

This PDF file includes:

  • Fig. S1. S. cerevisiae does not induce greater inflammation.
  • Fig. S2. S. cerevisiae leads to worsened intestinal barrier.
  • Fig. S3. S. cerevisiae induces purine metabolism.
  • Fig. S4. There is a positive correlation between elevated uric acid and ASCAs but not with anti-chromatin antibodies.
  • Fig. S5. S. cerevisiae does not exacerbate disease through NLRP3.
  • Table S1. Primer sets for qPCR.

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