Supplementary Materials

Supplementary Material for:

Intestinal commensal bacteria mediate lung mucosal immunity and promote resistance of newborn mice to infection

Jerilyn Gray, Katherine Oehrle, George Worthen, Theresa Alenghat, Jeffrey Whitsett, Hitesh Deshmukh*

*Corresponding author. Email: hitesh.deshmukh{at}cchmc.org

Published 8 February 2017, Sci. Transl. Med. 9, eaaf9412 (2017)
DOI: 10.1126/scitranslmed.aaf9412

This PDF file includes:

  • Fig. S1. Intestinal commensal bacteria promote resistance to S. pneumoniae in newborn mice via IL-22.
  • Fig. S2. Intestinal commensal bacteria direct postnatal trafficking of IL-22+ILC3 to murine newborn lung promoting resistance to pneumonia.
  • Fig. S3. Intestinal DCs mediate cross-talk between commensal bacteria and ILC3.
  • Table S1A. Relative abundance of different commensal bacteria in the intestine of ABX-free or ABX-exposed newborn mice.
  • Table S1B. Relative abundance of different commensal bacteria in the lungs of ABX-free or ABX-exposed newborn mice.
  • Table S2. Differentially expressed genes in the lungs of P4 ABX-free or ABX-exposed newborn mice.

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Other Supplementary Material for this manuscript includes the following:

  • Table S3 (Microsoft Excel format). Tabulated raw data.