Supplementary Materials

Supplementary Material for:

Tumor-homing cytotoxic human induced neural stem cells for cancer therapy

Juli R. Bagó, Onyi Okolie, Raluca Dumitru, Matthew G. Ewend, Joel S. Parker, Ryan Vander Werff, T. Michael Underhill, Ralf S. Schmid, C. Ryan Miller, Shawn D. Hingtgen*

*Corresponding author. Email: hingtgen{at}email.unc.edu

Published 1 February 2017, Sci. Transl. Med. 9, eaah6510 (2017)
DOI: 10.1126/scitranslmed.aah6510

This PDF file includes:

  • Legends for Movies S1 to S8

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). h-iNSCTE migration to GBM cells.
  • Movie S2 (.avi format). Single-cell tracings revealing the migratory paths of h-iNSCTE to GBM cells in vitro.
  • Movie S3 (.avi format). Rosetta tracings demonstrating the migration of h-iNSCTE to GBM cells in vitro.
  • Movie S4 (.avi format). Migration of human fibroblasts in the presence of GBM cells.
  • Movie S5 (.avi format). Single-cell tracings showing the movement of human fibroblasts cocultured with GBM cells in vitro.
  • Movie S6 (.avi format). Rosetta tracings showing the nonoriented movement of human fibroblasts in the presence of GBM cells.
  • Movie S7 (.avi format). Blockade of h-iNSCTE migration to GBM cells by anti-CXCR4 antibody.
  • Movie S8 (.avi format). Single-cell tracings showing the movement of human fibroblasts pretreated with anti-CXCR4 antibody and cocultured with GBM cells.