Supplementary Materials

Supplementary Material for:

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

Waseem Qasim,* Hong Zhan, Sujith Samarasinghe, Stuart Adams, Persis Amrolia, Sian Stafford, Katie Butler, Christine Rivat, Gary Wright, Kathy Somana, Sara Ghorashian, Danielle Pinner, Gul Ahsan, Kimberly Gilmour, Giovanna Lucchini, Sarah Inglott, William Mifsud, Robert Chiesa, Karl S. Peggs, Lucas Chan, Farzin Farzaneh, Adrian J. Thrasher, Ajay Vora, Martin Pule, Paul Veys

*Corresponding author. Email: w.qasim{at}

Published 25 January 2017, Sci. Transl. Med. 9, eaaj2013 (2017)
DOI: 10.1126/scitranslmed.aaj2013

This PDF file includes:

  • Fig. S1. Karyotype analysis and FISH.
  • Fig. S2. Bone marrow studies.
  • Fig. S3. Cytokine studies.
  • Fig. S4. Flow cytometry detection of UCART19 in subject 1.
  • Fig. S5. Skin histology in subject 1.
  • Table S1. Molecular characterization of gene editing using NGS across the TRAC, CD52, and 15 possible off-target loci.

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