Supplementary Materials

Supplementary Material for:

Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring

Roy Malka, David M. Nathan, John M. Higgins*

*Corresponding author. Email: john_higgins{at}hms.harvard.edu

Published 5 October 2016, Sci. Transl. Med. 8, 359ra130 (2016)
DOI: 10.1126/scitranslmed.aaf9304

This PDF file includes:

  • Materials and Methods
  • Fig. S1. Hemoglobin glycation in vivo and in vitro is controlled by glucose level (AG) and incubation time (MRBC).
  • Fig. S2. Model-based inference of AG from HbA1c reduces estimation errors by about 50%.
  • Fig. S3. Comparison of magnitudes of AG estimation errors using the standard regression method and the patient-specific model.
  • Fig. S4. Patient-specific linear regression of AG and HbA1c measurements.
  • References (4045)

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