Supplementary Materials

Supplementary Material for:

Tissue-engineered autologous grafts for facial bone reconstruction

Sarindr Bhumiratana, Jonathan C. Bernhard, David M. Alfi, Keith Yeager, Ryan E. Eton, Jonathan Bova, Forum Shah, Jeffrey M. Gimble, Mandi J. Lopez, Sidney B. Eisig, Gordana Vunjak-Novakovic*

*Corresponding author. Email: gv2131{at}columbia.edu

Published 15 June 2016, Sci. Transl. Med. 8, 343ra83 (2016)
DOI: 10.1126/scitranslmed.aad5904

This PDF file includes:

  • Methods
  • Fig. S1. Structural comparison of tissue-engineered graft and native explant.
  • Fig. S2. Regeneration of RCU.
  • Fig. S3. High-resolution Movat’s pentachrome stain of the ramus in the condylectomy group at 6 months.
  • Fig. S4. High-resolution Movat’s pentachrome stain of the ramus in the acellular scaffold group.
  • Fig. S5. High-resolution Movat’s pentachrome stain of the ramus in the tissue-engineered bone group.
  • Fig. S6. Condyle regeneration (posterior view and histologies).
  • Fig. S7. High-resolution Movat’s pentachrome stain of the condyle in the condylectomy group at 6 months.
  • Fig. S8. High-resolution Movat’s pentachrome stain of the ramus in the acellular scaffold group.
  • Fig. S9. High-resolution Movat’s pentachrome stain of the ramus in the tissue-engineered bone group.
  • Fig. S10. Ossification patterns in the condyle after tissue-engineered bone regeneration.
  • Fig. S11. Experimental setup for the three-point bending mechanical testing.
  • Table S1. Porcine real-time polymerase chain reaction (RT-PCR) primers.
  • Legends for Movies S1 and S2

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Assembly of bioreactor.
  • Movie S2 (.mp4 format). Finite element modeling of oxygen concentration.

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