Supplementary Materials

Supplementary Material for:

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

Kevin M. Vannella, Thirumalai R. Ramalingam, Lee A. Borthwick, Luke Barron, Kevin M. Hart, Robert W. Thompson, Kristen N. Kindrachuk, Allen W. Cheever, Sandra White, Alison L. Budelsky, Michael R. Comeau, Dirk E. Smith, Thomas A. Wynn*

*Corresponding author. Email: twynn{at}

Published 4 May 2016, Sci. Transl. Med. 8, 337ra65 (2016)
DOI: 10.1126/scitranslmed.aaf1938

This PDF file includes:

  • Fig. S1. Alarmin gene expression in the liver.
  • Fig. S2. Kinetics of alarmin gene expression in chronic HDM model.
  • Fig. S3. Neutralizing all three alarmins with mAbs during initiation and maintenance of type 2–driven allergy reduces inflammation and fibrosis.
  • Table S1. qPCR primer sequences.

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Other Supplementary Material for this manuscript includes the following: